The NFL continues with Week 16 games on Saturday, December 22, and here you can check out the best Bills vs. Bears betting pick and odds.
Chicago is hoping to avoid the eighth defeat in a row and Buffalo is looking for the sixth straight win when they meet at Soldier Field. The Bills are 9-point favorites on BetRivers NY Sportsbook, while the total is set at 40.5 points. These inter-conference rivals will meet for the first time since 2018.
Bills remain at the top of the AFC
The Buffalo Bills (11-3-0, 6-7-1 ATS) are on a five-game winning streak and are on a good course to finish the regular season as the AFC champions. Buffalo spent the previous two games at home, where they beat the divisional rivals New York Jets and Miami Dolphins. Both were one-score wins, but the latest against Miami was a thriller in which Tyler Bass scored a game-winning field goal as time expired to secure a 32-29 victory for the Bills.
Josh Allen completed 25 of 40 passes for 304 yards and four touchdowns. He also led the team in rushing yards with 77 on ten carries. Dawson Knox led the Bills in receiving yards with 98 and a touchdown on six catches; Stefon Diggs and Gabe Davis combined for 116 yards on nine receptions, while Quintin Morris, Nyheim Hines, and James Cook contributed a receiving TD apiece. On defense, Tremaine Edmunds and Matt Milano each had a game-high eight tackles.
LB Von Miller (knee), S Micah Hyde (neck), WR Jamison Crowder (ankle), and T Tommy Doyle (ACL) are out indefinitely and will not play on Saturday against Chicago.
Bears dropped to the bottom of the NFC
The Chicago Bears (3-11-0, 5-8-1 ATS) lost seven consecutive games and dropped to the last place in the NFC. Right now, only the Houston Texans have a worse record than the Bears, who fell short of the Philadelphia Eagles at home in the most recent defeat. Although a 25-20 result doesn’t implicate so, Philly controlled the game and deserved to win as the Eagles totaled 421 yards opposite Chicago’s 248.
Justin Fields completed 14 of 21 passes for 152 yards, two touchdowns, and no interceptions. He did lead all the runners with a game-high 95 yards on 15 carries, while David Montgomery had 53 rushing yards and a touchdown on 12 attempts. Montgomery also scored a receiving touchdown, just like Byron Pringle, who led the team with 39 receiving yards on two catches. Defensively, Nicholas Morrow was solid with a game-high 11 tackles.
LB Matthew Adams (calf) and WR Darnell Mooney (ankle) are out indefinitely. WR Equanimeous St. Brown (concussion), WR N’Keal Harry (back), WR Chase Claypool (knee), CB Jaylon Johnson (ribs), T Teven Jenkins (neck), and RB Khalil Herbert (hip) are questionable to face the Bills on Saturday.
11-3-2 ATS in the last 16 games vs. a team with a losing record 9-4-2 ATS in the last 15 games following an ATS loss 15-6-3 ATS in the last 24 games after accumulating more than 250 yards passing in their previous game
1-4 ATS in the last five games overall 1-6 ATS in the last seven home games vs. a team with a winning road record
Buffalo Bills vs. Chicago Bears Pick
Buffalo has the second-best defense in the NFL that is allowing 17.9 points per game, while Chicago has the third-worst D in the league that is surrendering 25.6 ppg. The Bills also have a better offense that is averaging 27.5 ppg opposite Chicago’s 20.7 ppg. Considering the form of these respective teams, there is no doubt the Bills are going to get a comfortable victory on Saturday. The Bears are not bad when it comes to pass defense, but are quite lenient in run defense as they allow 143.9 yards per contest. Buffalo should exploit that and do damage on the ground through Allen and Singletary.
Pick: Take the Bills at -7.5 (-120)
Chicago’s defense allowed 25+ points in each of the last seven games, while the Bears allowed 30+ in four of those seven. That’s an open invitation for the high-flying Bills to score plenty of points and multiple touchdowns on Saturday, and I am backing them to do so. Buffalos scored 20+ points in each of its previous six games, so I don’t think a 30+ point game here will be a problem for the visitors. Over is 10-2 in the Bills’ last 12 games after accumulating more than 350 total yards in their previous game, while Over is 7-1 in the Bears’ previous eight games overall.
Pick: Go Over 39.5 points (-120)